Treating Neuropathy with Platelet Rich Plasma

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Neuropathy is a medical term used to address nerve problems in the body. Nerves can get affected or damaged by diseases or injury. Neuropathy refers to malfunctions or general diseases of nerves. Neuropathy affects the Peripheral Nervous System more than the Central Nervous System of the body. Conditions like diabetes, vitamin deficiencies, infections, autoimmune attacks, genetic disorders, tumors and trauma may cause neuropathy.

Types of Neuropathy

  • Peripheral neuropathy
  • Cranial neuropathy
  • Autonomic neuropathy
  • Focal neuropathy

Platelet rich plasma

Blood contains platelets, red blood cells, white blood cells, and plasma. Blood platelets are best known for blood clotting functions. Blood platelets also hold hundreds of proteins known as growth factors. Growth factors are vital for the healing of injuries. Platelet- rich plasma contains many more platelets in comparison to blood. PRP contains 10 times more growth factors than normal blood plasma. PRP is prepared by drawing blood from the patient. The platelets are then eliminated from blood cells and centrifuged to increase the concentration of platelets. Now the increased platelets are combined to remaining blood and platelet rich plasma is ready to use for treatment.

Neuropathy treatment with platelet rich plasma

PRP treatment is one of the most growing technologies of medicine called regenerative medicine. PRP is being used in various areas of medicine including wound healing, neurosurgery, podiatry, heart surgery, and orthopedics. Now it is also available for treatment of neuropathic pain and Peripheral Neuropathy. Neuropathy pain is worse. Various drugs provide short term relief from neuropathic pain. Many drugs are not effective and may cause serious side effects. Most of the drugs are not able to provide permanent pain relief and healing effect. Research and some trials state that Platelet rich plasma, when injected to the painful site, promotes the natural healing process of the body and thus reduces the pain.

PRP holds growth factors, proteins and other essential components that direct the body to revive damaged tissues. During the clinical applications, PRP is injected into pain-originating sites. Platelet Rich Plasma when injected to the painful site, promotes natural healing in the body and thus reduces pain. During the clinical applications, PRP is injected into painful areas including joints, muscle injuries and ends of nerves inducing chronic neuropathic pain, reducing pain at these sites. Platelet rich plasma therapy has proved its effectiveness to end chronic neuropathic pain.

When PRP is introduced to the painful site, its growth factors release stem cells and promotes the healing process. Growth factors and stem cells encourage wound repair, axon regeneration and tissue remodeling. These result in a reduction in neuropathic pain. Repair and regeneration of damaged or injured nerves is a challenging task but researchers believe that PRP has the potential to promote growth. When PRP is injected to the affected nerves, it can increase sensation and boost nerve regeneration.


Clinical studies of PRP neuropathy treatment have shown remarkable results. Most patients reported meaningful pain reduction within the first two weeks of treatment. Many judgments disclose the use of ample regenerative potential of PRP. Further research is required to analyze the efficiency of PRP on nerve regeneration. The results support promising proofs for another operation of PRP in future.

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